Reversing bone loss by directing mesenchymal stem cells to bone
نویسندگان
چکیده
منابع مشابه
Reversing bone loss by directing mesenchymal stem cells to bone.
Bone regeneration by systemic transplantation of mesenchymal stem cells (MSCs) is problematic due to the inability to control the MSCs' commitment, growth, and differentiation into functional osteoblasts on the bone surface. Our research group has developed a method to direct the MSCs to the bone surface by conjugating a synthetic peptidomimetic ligand (LLP2A) that has high affinity for activat...
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Introduction Brain trauma is one of the most common causes of hospitalization, disability, and mortality of people aged 15 to 74 years in nowadays societies. On the other hand, nowadays, different categories of stem cells are used to treat different kinds of diseases. BM-MSCs, are center of scientific research because of their high differentiation and proliferation ability. Methods: Stem cel...
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Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...
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ژورنال
عنوان ژورنال: STEM CELLS
سال: 2013
ISSN: 1066-5099
DOI: 10.1002/stem.1461